MAEL antibody (AA 73-347) (Biotin)

Catalog No. ABIN8007340

The Biotin-conjugated Rabbit Polyclonal anti-MAEL antibody (ABIN8007340) specifically detects MAEL in ELISA, WB and IHC. The antibody is reactive with Human samples.

Quick Overview for MAEL antibody (AA 73-347) (Biotin) (ABIN8007340)

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEL antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MAEL Antibody (Biotin)

Binding Specificity: AA 73-347

Purpose: Anti-MAEL Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAEL recombinant protein (Position: E73-Q347).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAEL

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Alternative Name: MAEL

Background:

Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Gene Full Name: maelstrom spermatogenic transposon silencer

Gene ID: 84944

UniProt: Q96JY0