MAEL antibody (AA 73-347)

Catalog No. ABIN8007350

This Rabbit Polyclonal antibody specifically detects MAEL in ELISA, WB and FACS. It exhibits reactivity toward Human.

Quick Overview for MAEL antibody (AA 73-347) (ABIN8007350)

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEL antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-MAEL Antibody

Binding Specificity: AA 73-347

Purpose: Anti-MAEL Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-MAEL Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAEL recombinant protein (Position: E73-Q347).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAEL

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Alternative Name: MAEL

Background:

Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

Gene Full Name: maelstrom spermatogenic transposon silencer

Molecular Weight: 49 kDa

Gene ID: 84944

UniProt: Q96JY0