MDH2 antibody (AA 9-223) (HRP)

Catalog No. ABIN8007522

The Mouse Monoclonal anti-MDH2 antibody is suitable to detect MDH2 in samples from Human. It has been validated for WB, IHC and ELISA.

Quick Overview for MDH2 antibody (AA 9-223) (HRP) (ABIN8007522)

Target: MDH2 (Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MDH2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 5D8C1

Product Details anti-MDH2 Antibody (HRP)

Binding Specificity: AA 9-223

Purpose: Anti-MDH2 Antibody (monoclonal, 5D8C1) HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: Human MDH2 shares 97.7%,98.1% amino acid (aa) sequence identity with mouse,rat MDH2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MDH2 recombinant protein (Position: A9-L223). Human MDH2 shares 97.7% and 98.1% amino acid (aa) sequence identity with mouse and rat MDH2, respectively.

Isotype: IgG2b

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MDH2

Target: MDH2 (Malate Dehydrogenase 2, NAD (Mitochondrial) (MDH2))

Alternative Name: MDH2

Background:

Background: Malate dehydrogenase, mitochondrial also known as malate dehydrogenase 2 is an enzyme that in humans is encoded by the MDH2 gene. Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: malate dehydrogenase 2

Gene ID: 4191

UniProt: P40926