MAML1 antibody (AA 1-998) (FITC)

Catalog No. ABIN8007906

The Rabbit Polyclonal anti-MAML1 antibody is suitable to detect MAML1 in samples from Human. It has been validated for FACS.

Quick Overview for MAML1 antibody (AA 1-998) (FITC) (ABIN8007906)

Target: MAML1 (Mastermind-Like 1 (MAML1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAML1 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-MAML1 Antibody (FITC)

Binding Specificity: AA 1-998

Purpose: Anti-MAML1 Antibody FITC Conjugated

Predicted Reactivity: Human MAML1 shares 86.3% amino acid (aa) sequence identity with mouse MAML1.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAML1 recombinant protein (Position: M1-K998). Human MAML1 shares 86.3% amino acid (aa) sequence identity with mouse MAML1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MAML1

Target: MAML1 (Mastermind-Like 1 (MAML1))

Alternative Name: MAML1

Background:

Background: Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene. This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Gene Full Name: mastermind like transcriptional coactivator 1

Gene ID: 9794

UniProt: Q92585

Pathways: Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development