MAML1 antibody (AA 1-998)

Catalog No. ABIN8007911

This Rabbit Polyclonal antibody specifically detects MAML1 in ELISA, WB, FACS, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for MAML1 antibody (AA 1-998) (ABIN8007911)

Target: MAML1 (Mastermind-Like 1 (MAML1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAML1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-MAML1 Antibody

Binding Specificity: AA 1-998

Purpose: Anti-MAML1 Antibody

Predicted Reactivity: Human MAML1 shares 86.3% amino acid (aa) sequence identity with mouse MAML1.

Characteristics: Anti-MAML1 Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAML1 recombinant protein (Position: M1-K998). Human MAML1 shares 86.3% amino acid (aa) sequence identity with mouse MAML1.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MAML1

Target: MAML1 (Mastermind-Like 1 (MAML1))

Alternative Name: MAML1

Background:

Background: Mastermind-like protein 1 is a protein that in humans is encoded by the MAML1 gene. This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.

Gene Full Name: mastermind like transcriptional coactivator 1

Molecular Weight: 130 kDa

Gene ID: 9794

UniProt: Q92585

Pathways: Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development