MCPH1 antibody (AA 64-835) (Fluoro550)

Catalog No. ABIN8009939

This Rabbit Polyclonal antibody specifically detects MCPH1 in FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for MCPH1 antibody (AA 64-835) (Fluoro550) (ABIN8009939)

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCPH1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-MCPH1 Antibody (Fluoro550)

Binding Specificity: AA 64-835

Purpose: Anti-BRIT1/MCPH1 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BRIT1/MCPH1 recombinant protein (Position: Q64-Q835).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Alternative Name: MCPH1

Background:

Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Gene Full Name: microcephalin 1

Gene ID: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance