MCPH1 antibody (AA 64-835) (Fluoro594)

Catalog No. ABIN8009940

The Rabbit Polyclonal anti-MCPH1 antibody is suitable to detect MCPH1 in samples from Human and Mouse. It has been validated for WB, ELISA, IF, ICC and FACS.

Quick Overview for MCPH1 antibody (AA 64-835) (Fluoro594) (ABIN8009940)

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCPH1 antibody is conjugated to Fluoro594

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Product Details anti-MCPH1 Antibody (Fluoro594)

Binding Specificity: AA 64-835

Purpose: Anti-BRIT1/MCPH1 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human BRIT1/MCPH1 recombinant protein (Position: Q64-Q835).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Alternative Name: MCPH1

Background:

Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Gene Full Name: microcephalin 1

Gene ID: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance