Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (N-Term) antibody (Fluoro488)

Catalog No. ABIN8010808

The Fluoro488-conjugated Rabbit Polyclonal anti-Mitochondrially Encoded NADH Dehydrogenase 4 antibody (ABIN8010808) specifically detects Mitochondrially Encoded NADH Dehydrogenase 4 in FACS. The antibody is reactive with Rat samples.

Quick Overview for Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4) (N-Term) antibody (Fluoro488) (ABIN8010808)

Target: Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Fluoro488

Application: Flow Cytometry (FACS)

Product Details

Binding Specificity: N-Term

Purpose: Anti-ND4/Mtnd4 Antibody Fluoro488 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of rat ND4/Mtnd4, which shares 82.3% amino acid (aa) sequence identity with mouse ND4/Mtnd4.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details

Target: Mitochondrially Encoded NADH Dehydrogenase 4 (MT-ND4)

Alternative Name: Mtnd4

Background:

Background: NADH-ubiquinone oxidoreductase chain 4 is a protein that in humans is encoded by the mitochondrial gene MT-ND4. The ND4 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain. Variations in the MT-ND4 gene are associated with age-related macular degeneration (AMD), Leber's hereditary optic neuropathy (LHON), mesial temporal lobe epilepsy (MTLE) and cystic fibrosis.

Gene Full Name: NADH dehydrogenase subunit 4

Gene ID: 26201

UniProt: P05508