MAPK11 antibody (AA 230-364) (APC)

Catalog No. ABIN8010912

The Rabbit Polyclonal anti-MAPK11 antibody is suitable to detect MAPK11 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for MAPK11 antibody (AA 230-364) (APC) (ABIN8010912)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK11 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-MAPK11 Antibody (APC)

Binding Specificity: AA 230-364

Purpose: Anti-MAPK11 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAPK11 recombinant protein (Position: D230-Q364).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Alternative Name: MAPK11

Background:

Background: Mitogen-activated protein kinase 11 is an enzyme that in humans is encoded by the MAPK11 gene. This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants.

Gene Full Name: mitogen-activated protein kinase 11

Gene ID: 5600

UniProt: Q15759

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins