NEIL3 antibody (AA 244-585) (Fluoro550)

Catalog No. ABIN8014188

The Rabbit Polyclonal anti-NEIL3 antibody is suitable to detect NEIL3 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for NEIL3 antibody (AA 244-585) (Fluoro550) (ABIN8014188)

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEIL3 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-NEIL3 Antibody (Fluoro550)

Binding Specificity: AA 244-585

Purpose: Anti-NEIL3 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NEIL3 recombinant protein (Position: K244-K585).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NEIL3

Target: NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))

Alternative Name: NEIL3

Background:

Background: Nei endonuclease VIII-like 3 (E. coli) is a protein in humans that is encoded by the NEIL3 gene. NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.

Gene Full Name: nei like DNA glycosylase 3

Gene ID: 55247

UniProt: Q8TAT5

Pathways: DNA Damage Repair