NEFM antibody (AA 125-916) (Fluoro594)

Catalog No. ABIN8014728

The Rabbit Polyclonal anti-NEFM antibody is suitable to detect NEFM in samples from Human, Rat and Mouse. It has been validated for FACS.

Quick Overview for NEFM antibody (AA 125-916) (Fluoro594) (ABIN8014728)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFM antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-NEFM Antibody (Fluoro594)

Binding Specificity: AA 125-916

Purpose: Anti-NF-M/NEFM Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NF-M,NEFMshares 72.3%,72% amino acid (aa) sequence identity with mouse,rat NF-M,NEFM,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NF-M/NEFM recombinant protein (Position: Q125-D916). Human NF-M/NEFMshares 72.3% and 72% amino acid (aa) sequence identity with mouse and rat NF-M/NEFM, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Alternative Name: NEFM

Background:

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: neurofilament medium chain

Gene ID: 4741

UniProt: P07197

Pathways: Brown Fat Cell Differentiation