NEUROD1 antibody (N-Term) (Fluoro488)

Catalog No. ABIN8014891

The Fluoro488-conjugated Rabbit Polyclonal anti-NEUROD1 antibody (ABIN8014891) specifically detects NEUROD1 in FACS. The antibody is reactive with Human and Rat samples.

Quick Overview for NEUROD1 antibody (N-Term) (Fluoro488) (ABIN8014891)

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEUROD1 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-NEUROD1 Antibody (Fluoro488)

Binding Specificity: N-Term

Purpose: Anti-NEUROD1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NEUROD1 shares 90.9% amino acid (aa) sequence identity with both mouse,rat NEUROD1.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human NEUROD1. Human NEUROD1 shares 90.9% amino acid (aa) sequence identity with both mouse and rat NEUROD1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NEUROD1

Target: NEUROD1 (Neuronal Differentiation 1 (NEUROD1))

Alternative Name: NEUROD1

Background:

Background: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.

Gene Full Name: neuronal differentiation 1

Gene ID: 4760

UniProt: Q13562

Pathways: Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis