NHP2 antibody (AA 21-136) (Fluoro488)

Catalog No. ABIN8015375

This Rabbit Polyclonal antibody specifically detects NHP2 in FACS. It exhibits reactivity toward Human.

Quick Overview for NHP2 antibody (AA 21-136) (Fluoro488) (ABIN8015375)

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NHP2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-NHP2 Antibody (Fluoro488)

Binding Specificity: AA 21-136

Purpose: Anti-NHP2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NHP2 recombinant protein (Position: E21-Q136).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NHP2

Target: NHP2 (NHP2 Ribonucleoprotein (NHP2))

Alternative Name: NHP2

Background:

Background: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants.

Gene Full Name: NHP2 ribonucleoprotein

Gene ID: 55651

UniProt: Q9NX24

Pathways: Telomere Maintenance