NKX3-1 antibody (N-Term) (Cy3)

Catalog No. ABIN8015792

This Rabbit Polyclonal antibody specifically detects NKX3-1 in FACS. It exhibits reactivity toward Human.

Quick Overview for NKX3-1 antibody (N-Term) (Cy3) (ABIN8015792)

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-1 antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-NKX3-1 Antibody (Cy3)

Binding Specificity: N-Term

Purpose: Anti-NKX3-1 Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human NKX3-1 shares 78.9% amino acid (aa) sequence identity with mouse NKX3-1.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human NKX3-1. Human NKX3-1 shares 78.9% amino acid (aa) sequence identity with mouse NKX3-1.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Alternative Name: NKX3-1

Background:

Background: This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

Gene Full Name: NK3 homeobox 1

Gene ID: 4824

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus