NKX3-1 antibody (N-Term) (Biotin)

Catalog No. ABIN8015802

The Rabbit Polyclonal anti-NKX3-1 antibody is suitable to detect NKX3-1 in samples from Mouse and Rat. It has been validated for IHC, WB and ELISA.

Quick Overview for NKX3-1 antibody (N-Term) (Biotin) (ABIN8015802)

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX3-1 antibody is conjugated to Biotin

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Product Details anti-NKX3-1 Antibody (Biotin)

Binding Specificity: N-Term

Purpose: Anti-NKX3-1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse NKX3-1 shares 80% amino acid (aa) sequence identity with human NKX3-1.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse NKX3-1. Mouse NKX3-1 shares 80% amino acid (aa) sequence identity with human NKX3-1.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Alternative Name: NKX3-1

Background:

Background: This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

Gene Full Name: NK3 homeobox 1

Gene ID: 18095

UniProt: P97436

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus