NUP88 antibody (AA 91-584) (PE)

Catalog No. ABIN8017407

The Rabbit Polyclonal anti-NUP88 antibody is suitable to detect NUP88 in samples from Human. It has been validated for FACS.

Quick Overview for NUP88 antibody (AA 91-584) (PE) (ABIN8017407)

Target: NUP88 (Nucleoporin 88kDa (NUP88))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP88 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-NUP88 Antibody (PE)

Binding Specificity: AA 91-584

Purpose: Anti-NUP88 Antibody PE Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human NUP88 shares 89.8%,89.9% amino acid (aa) sequence identity with mouse,rat NUP88,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NUP88 recombinant protein (Position: E91-K584). Human NUP88 shares 89.8% and 89.9% amino acid (aa) sequence identity with mouse and rat NUP88, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for NUP88

Target: NUP88 (Nucleoporin 88kDa (NUP88))

Alternative Name: NUP88

Background:

Background: Nucleoporin 88 (Nup88) is a protein that in humans is encoded by the NUP88 gene. The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: nucleoporin 88

Gene ID: 4927

UniProt: Q99567

Pathways: SARS-CoV-2 Protein Interactome