NUP88 antibody (AA 91-584)
Quick Overview for NUP88 antibody (AA 91-584) (ABIN8017409)
Target
See all NUP88 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Binding Specificity
- AA 91-584
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Purpose
- Anti-NUP88 Antibody
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Cross-Reactivity (Details)
- No cross reactivity with other proteins.
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Predicted Reactivity
- Human NUP88 shares 89.8%,89.9% amino acid (aa) sequence identity with mouse,rat NUP88,respectively.
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Characteristics
- Anti-NUP88 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human NUP88 recombinant protein (Position: E91-K584). Human NUP88 shares 89.8% and 89.9% amino acid (aa) sequence identity with mouse and rat NUP88, respectively.
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Isotype
- IgG
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Application Notes
- Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Storage
- 4 °C,-20 °C
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Storage Comment
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Expiry Date
- 12 months
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- NUP88 (Nucleoporin 88kDa (NUP88))
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Alternative Name
- NUP88
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Background
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Background: Nucleoporin 88 (Nup88) is a protein that in humans is encoded by the NUP88 gene. The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: nucleoporin 88
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Molecular Weight
- 84 kDa
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Gene ID
- 4927
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UniProt
- Q99567
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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