PAK4 antibody (C-Term) (HRP)
Quick Overview for PAK4 antibody (C-Term) (HRP) (ABIN8019003)
Target
See all PAK4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purpose
- Anti-PAK4 Antibody HRP Conjugated
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Cross-Reactivity (Details)
- No cross-reactivity with other proteins
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Purification
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human PAK4.
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Isotype
- IgG
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Application Notes
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Storage
- -20 °C
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Storage Comment
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- PAK4 (P21-Activated Kinase 4 (PAK4))
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Alternative Name
- PAK4
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Background
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Background: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene Full Name: p21 (RAC1) activated kinase 4
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Gene ID
- 10298
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UniProt
- O96013
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Pathways
- RTK Signaling
Target
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