Paired Box 3 antibody (AA 306-420) (APC)

Catalog No. ABIN8019092

This Rabbit Polyclonal antibody specifically detects Paired Box 3 in FACS. It exhibits reactivity toward Human.

Quick Overview for Paired Box 3 antibody (AA 306-420) (APC) (ABIN8019092)

Target: Paired Box 3 (PAX3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paired Box 3 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-Paired Box 3 Antibody (APC)

Binding Specificity: AA 306-420

Purpose: Anti-PAX3 Antibody APC Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PAX3 recombinant protein (Position: Q306-E420). Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3

Background:

Background: The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors. This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Gene Full Name: paired box 3

Gene ID: 5077

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation