Paired Box 3 antibody (AA 306-420)

Catalog No. ABIN8019095

This Rabbit Polyclonal antibody specifically detects Paired Box 3 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for Paired Box 3 antibody (AA 306-420) (ABIN8019095)

Target: Paired Box 3 (PAX3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-Paired Box 3 Antibody

Binding Specificity: AA 306-420

Purpose: Anti-PAX3 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.

Characteristics: Anti-PAX3 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PAX3 recombinant protein (Position: Q306-E420). Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3

Background:

Background: The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors. This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Gene Full Name: paired box 3

Molecular Weight: 69 kDa

Gene ID: 5077

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation