PRCC antibody (C-Term) (HRP)

Catalog No. ABIN8019423

The Rabbit Polyclonal anti-PRCC antibody is suitable to detect PRCC in samples from Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for PRCC antibody (C-Term) (HRP) (ABIN8019423)

Target: PRCC (Papillary Renal Cell Carcinoma (Translocation-Associated) (PRCC))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRCC antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PRCC Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-PRCC Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PRCC.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRCC

Target: PRCC (Papillary Renal Cell Carcinoma (Translocation-Associated) (PRCC))

Alternative Name: PRCC

Background:

Background: This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X,1)(p11,q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.

Gene Full Name: proline rich mitotic checkpoint control factor

Gene ID: 5546

UniProt: Q92733