PPIE antibody (AA 1-301) (Fluoro550)

Catalog No. ABIN8020397

This Mouse Monoclonal antibody specifically detects PPIE in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PPIE antibody (AA 1-301) (Fluoro550) (ABIN8020397)

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This PPIE antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Clone: 7F2

Product Details anti-PPIE Antibody (Fluoro550)

Binding Specificity: AA 1-301

Purpose: Anti-Cyclophilin E/PPIE Antibody (monoclonal, 7F2) Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Cyclophilin E/PPIE recombinant protein (Position: M1-V301).

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PPIE

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Alternative Name: PPIE

Background:

Background: Peptidylprolyl isomerase E (cyclophilin E), also known as PPIE, is an enzyme which in humans is encoded by the PPIE gene on chromosome 1. The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified.

Gene Full Name: peptidylprolyl isomerase E

Gene ID: 10450

UniProt: Q9UNP9