Phenylalanine Hydroxylase antibody (AA 71-208) (HRP)

Catalog No. ABIN8021071

The HRP-conjugated Rabbit Polyclonal anti-Phenylalanine Hydroxylase antibody (ABIN8021071) specifically detects Phenylalanine Hydroxylase in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Phenylalanine Hydroxylase antibody (AA 71-208) (HRP) (ABIN8021071)

Target: Phenylalanine Hydroxylase

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phenylalanine Hydroxylase antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Phenylalanine Hydroxylase Antibody (HRP)

Binding Specificity: AA 71-208

Purpose: Anti-PAH Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human PAH recombinant protein (Position: R71-H208). Human PAH shares 89.1%,88.4% amino acid (aa) sequence identity with mouse,rat PAH,respectively.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human PAH recombinant protein (Position: R71-H208). Human PAH shares 89.1% and 88.4% amino acid (aa) sequence identity with mouse and rat PAH, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Phenylalanine Hydroxylase

Target: Phenylalanine Hydroxylase

Alternative Name: PAH

Background:

Background: Phenylalanine hydroxylase (PAH) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine. It is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin (BH4, a pteridine cofactor) and a non-heme iron for catalysis. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.

Gene Full Name: phenylalanine hydroxylase

Gene ID: 5053

UniProt: P00439