PEMT antibody (C-Term) (Fluoro550)

Catalog No. ABIN8021225

This Rabbit Polyclonal antibody specifically detects PEMT in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PEMT antibody (C-Term) (Fluoro550) (ABIN8021225)

Target: PEMT (Phosphatidylethanolamine N-Methyltransferase (PEMT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEMT antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-PEMT Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-PEMT Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human PEMT shares 94.7%,84.2% amino acid (aa) sequence identity with mouse,rat PEMT,respectively.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PEMT. Human PEMT shares 94.7% and 84.2% amino acid (aa) sequence identity with mouse and rat PEMT, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PEMT

Target: PEMT (Phosphatidylethanolamine N-Methyltransferase (PEMT))

Alternative Name: PEMT

Background:

Background: Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Gene Full Name: phosphatidylethanolamine N-methyltransferase

Gene ID: 10400

UniProt: Q9UBM1