PIGV antibody (AA 26-470)

Catalog No. ABIN8021298

The Rabbit Polyclonal anti-PIGV antibody is suitable to detect PIGV in samples from Human. It has been validated for ELISA, WB and FACS.

Quick Overview for PIGV antibody (AA 26-470) (ABIN8021298)

Target: PIGV (Phosphatidylinositol Glycan Anchor Biosynthesis, Class V (PIGV))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGV antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-PIGV Antibody

Binding Specificity: AA 26-470

Purpose: Anti-PIGV Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PIGV Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PIGV recombinant protein (Position: Q26-Y470).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PIGV

Target: PIGV (Phosphatidylinositol Glycan Anchor Biosynthesis, Class V (PIGV))

Alternative Name: PIGV

Background:

Background: GPI mannosyltransferase 2 is an enzyme that in humans is encoded by the PIGV gene. This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia cognitive disability syndrome. Alternatively spliced transcript variants have been observed for this gene.

Gene Full Name: phosphatidylinositol glycan anchor biosynthesis class V

Molecular Weight: 60 kDa

Gene ID: 55650

UniProt: Q9NUD9

Pathways: Inositol Metabolic Process