PDE10A antibody (AA 515-779) (Fluoro550)

Catalog No. ABIN8021391

The Rabbit Polyclonal anti-PDE10A antibody is suitable to detect PDE10A in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for PDE10A antibody (AA 515-779) (Fluoro550) (ABIN8021391)

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE10A antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-PDE10A Antibody (Fluoro550)

Binding Specificity: AA 515-779

Purpose: Anti-PDE10A Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDE10A recombinant protein (Position: H515-D779).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDE10A

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Alternative Name: PDE10A

Background:

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.

Gene Full Name: phosphodiesterase 10A

Gene ID: 10846

UniProt: Q9Y233

Pathways: cAMP Metabolic Process