PITRM1 antibody (AA 33-1037) (APC)

Catalog No. ABIN8022641

This Rabbit Polyclonal antibody specifically detects PITRM1 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for PITRM1 antibody (AA 33-1037) (APC) (ABIN8022641)

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PITRM1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-PITRM1 Antibody (APC)

Binding Specificity: AA 33-1037

Purpose: Anti-PITRM1 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PITRM1 recombinant protein (Position: A33-K1037).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PITRM1

Target: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Alternative Name: PITRM1

Background:

Background: Pitrilysin metallopeptidase 1 also known as presequence protease, mitochondrial (PreP) and metalloprotease 1 (MTP-1) is an enzyme that in humans is encoded by the PITRM1 gene. The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease.

Gene Full Name: pitrilysin metallopeptidase 1

Gene ID: 10531

UniProt: Q5JRX3

Pathways: PI3K-Akt Signaling, SARS-CoV-2 Protein Interactome