POLM antibody (AA 36-481) (Fluoro594)

Catalog No. ABIN8024169

The Rabbit Polyclonal anti-POLM antibody is suitable to detect POLM in samples from Human. It has been validated for WB, ELISA and IP.

Quick Overview for POLM antibody (AA 36-481) (Fluoro594) (ABIN8024169)

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLM antibody is conjugated to Fluoro594

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-POLM Antibody (Fluoro594)

Binding Specificity: AA 36-481

Purpose: Anti-POLM Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human POLM shares 76.5% amino acid (aa) sequence identity with mouse POLM.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human POLM recombinant protein (Position: E36-H481). Human POLM shares 76.5% amino acid (aa) sequence identity with mouse POLM.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunoprecipitation, 0.5-2 μg/mL, Human ELISA, 0.1-0.5 μg/mL

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for POLM

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Alternative Name: POLM

Background:

Background: Predicted to enable DNA-directed DNA polymerase activity. Predicted to be involved in double-strand break repair via nonhomologous end joining. Predicted to act upstream of or within B cell differentiation and somatic hypermutation of immunoglobulin genes. Predicted to be located in nucleoplasm. Predicted to be active in nucleus.

Gene Full Name: DNA polymerase mu

Gene ID: 27434

UniProt: Q9NP87

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response