PDCD6 antibody (N-Term) (Fluoro594)

Catalog No. ABIN8025611

This Rabbit Polyclonal antibody specifically detects PDCD6 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDCD6 antibody (N-Term) (Fluoro594) (ABIN8025611)

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD6 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-PDCD6 Antibody (Fluoro594)

Binding Specificity: N-Term

Purpose: Anti-ALG2/PDCD6 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human ALG2,PDCD6 shares 100% amino acid (aa) sequence identity with both mouse,rat ALG2,PDCD6.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ALG2/PDCD6. Human ALG2/PDCD6 shares 100% amino acid (aa) sequence identity with both mouse and rat ALG2/PDCD6.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PDCD6

Target: PDCD6 (Programmed Cell Death 6 (PDCD6))

Alternative Name: PDCD6

Background:

Background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.

Gene Full Name: programmed cell death 6

Gene ID: 10016

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity