PCDHGA2 antibody (AA 132-444) (Biotin)

Catalog No. ABIN8028736

The Biotin-conjugated Rabbit Polyclonal anti-PCDHGA2 antibody (ABIN8028736) specifically detects PCDHGA2 in WB, IHC and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PCDHGA2 antibody (AA 132-444) (Biotin) (ABIN8028736)

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGA2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PCDHGA2 Antibody (Biotin)

Binding Specificity: AA 132-444

Purpose: Anti-PCDHGA2 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHGA2 recombinant protein (Position: R132-D444). Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PCDHGA2

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Alternative Name: PCDHGA2

Background:

Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Full Name: protocadherin gamma subfamily A, 2

Gene ID: 56113

UniProt: Q9Y5H1