PCDHGA2 antibody (AA 132-444)

Catalog No. ABIN8028746

This Rabbit Polyclonal antibody specifically detects PCDHGA2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for PCDHGA2 antibody (AA 132-444) (ABIN8028746)

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Carrier-free

Product Details anti-PCDHGA2 Antibody

Binding Specificity: AA 132-444

Purpose: Anti-PCDHGA2 Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Characteristics: Anti-PCDHGA2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PCDHGA2 recombinant protein (Position: R132-D444). Human PCDHGA2 shares 60.3% amino acid (aa) sequence identity with mouse PCDHGA2.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PCDHGA2

Target: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Alternative Name: PCDHGA2

Background:

Background: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Full Name: protocadherin gamma subfamily A, 2

Molecular Weight: 90 kDa

Gene ID: 56113

UniProt: Q9Y5H1