PCDH15 antibody (C-Term) (Fluoro550)

Catalog No. ABIN8028772

The Fluoro550-conjugated Rabbit Polyclonal anti-PCDH15 antibody (ABIN8028772) specifically detects PCDH15 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PCDH15 antibody (C-Term) (Fluoro550) (ABIN8028772)

Target: PCDH15 (Protocadherin-15 (PCDH15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH15 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-PCDH15 Antibody (Fluoro550)

Binding Specificity: C-Term

Purpose: Anti-PCDH15 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PCDH15, identical to the related mouse and rat sequences.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for PCDH15

Target: PCDH15 (Protocadherin-15 (PCDH15))

Alternative Name: PCDH15

Background:

Background: Protocadherin-15 is a protein that in humans is encoded by the PCDH15 gene. This gene is mapped to 10q21.1. This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur.

Gene Full Name: protocadherin related 15

Gene ID: 65217

UniProt: Q96QU1

Pathways: Sensory Perception of Sound