PDPR antibody (AA 155-655)

Catalog No. ABIN8029407

The Rabbit Polyclonal anti-PDPR antibody is suitable to detect PDPR in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for PDPR antibody (AA 155-655) (ABIN8029407)

Target: PDPR (Pyruvate Dehydrogenase Phosphatase Regulatory Subunit (PDPR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDPR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Grade: Carrier-free

Product Details anti-PDPR Antibody

Binding Specificity: AA 155-655

Purpose: Anti-PDPR Antibody

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human PDPR shares 94.4% amino acid (aa) sequence identity with mouse PDPR.

Characteristics: Anti-PDPR Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PDPR recombinant protein (Position: E155-E655). Human PDPR shares 94.4% amino acid (aa) sequence identity with mouse PDPR.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PDPR

Target: PDPR (Pyruvate Dehydrogenase Phosphatase Regulatory Subunit (PDPR))

Alternative Name: PDPR

Background:

Background: Pyruvate dehydrogenase phosphatase regulatory subunit is a protein that in humans is encoded by the PDPR gene. Pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and links glycolysis to the tricarboxylic acid cycle and fatty acid synthesis. The dephosphorylation and reactivation of PDC is catalyzed by pyruvate dehydrogenase phosphatase (PDP). The dimeric PDP has a catalytic subunit and a regulatory subunit. This gene encodes the FAD-containing regulatory subunit of PDP. The encoded protein acts to decrease the sensitivity of the PDP catalytic subunit to magnesium ions. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: pyruvate dehydrogenase phosphatase regulatory subunit

Molecular Weight: 99 kDa

Gene ID: 55066

UniProt: Q8NCN5