QPRT antibody (AA 24-297) (HRP)

Catalog No. ABIN8029503

The Rabbit Polyclonal anti-QPRT antibody is suitable to detect QPRT in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for QPRT antibody (AA 24-297) (HRP) (ABIN8029503)

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QPRT antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-QPRT Antibody (HRP)

Binding Specificity: AA 24-297

Purpose: Anti-QPRT Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human QPRT recombinant protein (Position: R24-H297).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for QPRT

Target: QPRT (Quinolinate Phosphoribosyltransferase (QPRT))

Alternative Name: QPRT

Background:

Background: This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.

Gene Full Name: quinolinate phosphoribosyltransferase

Gene ID: 23475

UniProt: Q15274