REPS2 antibody (AA 76-564) (APC)

Catalog No. ABIN8030323

The APC-conjugated Rabbit Polyclonal anti-REPS2 antibody (ABIN8030323) specifically detects REPS2 in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for REPS2 antibody (AA 76-564) (APC) (ABIN8030323)

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This REPS2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-REPS2 Antibody (APC)

Binding Specificity: AA 76-564

Purpose: Anti-REPS2 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human REPS2 shares 88.4% amino acid (aa) sequence identity with mouse REPS2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human REPS2 recombinant protein (Position: A76-K564). Human REPS2 shares 88.4% amino acid (aa) sequence identity with mouse REPS2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for REPS2

Target: REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))

Alternative Name: REPS2

Background:

Background: The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: RALBP1 associated Eps domain containing 2

Gene ID: 9185

UniProt: Q8NFH8

Pathways: EGFR Signaling Pathway