RP2 antibody (AA 244-348) (Fluoro647)

Catalog No. ABIN8031738

The Mouse Monoclonal anti-RP2 antibody is suitable to detect RP2 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for RP2 antibody (AA 244-348) (Fluoro647) (ABIN8031738)

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This RP2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Clone: 3D7

Product Details anti-RP2 Antibody (Fluoro647)

Binding Specificity: AA 244-348

Purpose: Anti-RP2 Antibody (monoclonal, 3D7) Fluoro647 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human RP2recombinant protein (Position: D244-M348).

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Alternative Name: RP2

Background:

Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death.The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

Gene Full Name: RP2 activator of ARL3 GTPase

Gene ID: 6102

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process