RBBP6 antibody (AA 19-1581) (Fluoro488)

Catalog No. ABIN8031810

The Rabbit Polyclonal anti-RBBP6 antibody is suitable to detect RBBP6 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for RBBP6 antibody (AA 19-1581) (Fluoro488) (ABIN8031810)

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP6 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-RBBP6 Antibody (Fluoro488)

Binding Specificity: AA 19-1581

Purpose: Anti-RBBP6 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human RBBP6 shares 89.5% amino acid (aa) sequence identity with mouse RBBP6.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RBBP6 recombinant protein (Position: F19-E1581). Human RBBP6 shares 89.5% amino acid (aa) sequence identity with mouse RBBP6.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RBBP6

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Alternative Name: RBBP6

Background:

Background: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Gene Full Name: RB binding protein 6, ubiquitin ligase

Gene ID: 5930

UniProt: Q7Z6E9

Pathways: Regulatory RNA Pathways