RBBP6 antibody (AA 19-1581) (HRP)

Catalog No. ABIN8031814

The HRP-conjugated Rabbit Polyclonal anti-RBBP6 antibody (ABIN8031814) specifically detects RBBP6 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RBBP6 antibody (AA 19-1581) (HRP) (ABIN8031814)

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBBP6 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RBBP6 Antibody (HRP)

Binding Specificity: AA 19-1581

Purpose: Anti-RBBP6 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human RBBP6 shares 89.5% amino acid (aa) sequence identity with mouse RBBP6.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RBBP6 recombinant protein (Position: F19-E1581). Human RBBP6 shares 89.5% amino acid (aa) sequence identity with mouse RBBP6.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RBBP6

Target: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Alternative Name: RBBP6

Background:

Background: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Gene Full Name: RB binding protein 6, ubiquitin ligase

Gene ID: 5930

UniProt: Q7Z6E9

Pathways: Regulatory RNA Pathways