RYR2 antibody (AA 1293-1423) (Fluoro488)

Catalog No. ABIN8034175

The Fluoro488-conjugated Rabbit Polyclonal anti-RYR2 antibody (ABIN8034175) specifically detects RYR2 in FACS. The antibody is reactive with Human samples.

Quick Overview for RYR2 antibody (AA 1293-1423) (Fluoro488) (ABIN8034175)

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYR2 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-RYR2 Antibody (Fluoro488)

Binding Specificity: AA 1293-1423

Purpose: Anti-RYR2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human RYR2 recombinant protein (Position: Q1293-T1423).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for RYR2

Target: RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Alternative Name: RYR2

Background:

Background: Ryanodine receptor 2 (RYR2) is a protein found primarily in cardiac muscle. In humans, it is encoded by the RYR2 gene. This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

Gene Full Name: ryanodine receptor 2

Gene ID: 6262

UniProt: Q92736

Pathways: Myometrial Relaxation and Contraction