SUN2 antibody (AA 31-695) (Fluoro488)

Catalog No. ABIN8034417

The Rabbit Polyclonal anti-SUN2 antibody is suitable to detect SUN2 in samples from Human. It has been validated for WB, IHC, ELISA, IF and ICC.

Quick Overview for SUN2 antibody (AA 31-695) (Fluoro488) (ABIN8034417)

Target: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUN2 antibody is conjugated to Fluoro488

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-SUN2 Antibody (Fluoro488)

Binding Specificity: AA 31-695

Purpose: Anti-SUN2 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SUN2 recombinant protein (Position: Q31-L695).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SUN2

Target: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Alternative Name: SUN2

Background:

Background: SUN1 and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins located in the outer nuclear membrane (ONM). The LINC complex provides a connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity.

Gene Full Name: Sad1 and UNC84 domain containing 2

Gene ID: 25777

UniProt: Q9UH99

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection