SRP72 antibody (AA 40-460) (Fluoro488)

Catalog No. ABIN8037322

The Fluoro488-conjugated Rabbit Polyclonal anti-SRP72 antibody (ABIN8037322) specifically detects SRP72 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SRP72 antibody (AA 40-460) (Fluoro488) (ABIN8037322)

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP72 antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SRP72 Antibody (Fluoro488)

Binding Specificity: AA 40-460

Purpose: Anti-SRP72 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SRP72 recombinant protein (Position: I40-Y460).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SRP72

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Alternative Name: SRP72

Background:

Background: This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: signal recognition particle 72

Gene ID: 6731

UniProt: O76094

Pathways: SARS-CoV-2 Protein Interactome