SREBF chaperone antibody (AA 1224-1279) (Fluoro488)

Catalog No. ABIN8042164

The Fluoro488-conjugated Rabbit Polyclonal anti-SREBF chaperone antibody (ABIN8042164) specifically detects SREBF chaperone in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SREBF chaperone antibody (AA 1224-1279) (Fluoro488) (ABIN8042164)

Target: SREBF chaperone (SCAP)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is conjugated to Fluoro488

Application: Flow Cytometry (FACS)

Product Details anti-SREBF chaperone Antibody (Fluoro488)

Binding Specificity: AA 1224-1279

Purpose: Anti-SCAP Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SCAP shares 100% amino acid (aa) sequence identity with both mouse,rat SCAP.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCAP recombinant protein (Position: F1224-D1279). Human SCAP shares 100% amino acid (aa) sequence identity with both mouse and rat SCAP.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP

Background:

Background: This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants.

Gene Full Name: SREBF chaperone

Gene ID: 22937

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome