SREBF chaperone antibody (AA 1224-1279) (HRP)

Catalog No. ABIN8042168

This Rabbit Polyclonal antibody specifically detects SREBF chaperone in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SREBF chaperone antibody (AA 1224-1279) (HRP) (ABIN8042168)

Target: SREBF chaperone (SCAP)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SREBF chaperone Antibody (HRP)

Binding Specificity: AA 1224-1279

Purpose: Anti-SCAP Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SCAP shares 100% amino acid (aa) sequence identity with both mouse,rat SCAP.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCAP recombinant protein (Position: F1224-D1279). Human SCAP shares 100% amino acid (aa) sequence identity with both mouse and rat SCAP.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP

Background:

Background: This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants.

Gene Full Name: SREBF chaperone

Gene ID: 22937

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome