SOX10 antibody (AA 178-301) (Fluoro647)

Catalog No. ABIN8042215

The Fluoro647-conjugated Rabbit Polyclonal anti-SOX10 antibody (ABIN8042215) specifically detects SOX10 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SOX10 antibody (AA 178-301) (Fluoro647) (ABIN8042215)

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX10 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-SOX10 Antibody (Fluoro647)

Binding Specificity: AA 178-301

Purpose: Anti-SOX10 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOX10 recombinant protein (Position: R178-L301).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for SOX10

Target: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Alternative Name: SOX10

Background:

Background: Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Gene Full Name: SRY-box transcription factor 10

Gene ID: 6663

UniProt: P56693

Pathways: Chromatin Binding