UBA2 antibody (AA 449-564) (HRP)

Catalog No. ABIN8043474

The Mouse Monoclonal anti-UBA2 antibody is suitable to detect UBA2 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for UBA2 antibody (AA 449-564) (HRP) (ABIN8043474)

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This UBA2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 5H11

Product Details anti-UBA2 Antibody (HRP)

Binding Specificity: AA 449-564

Purpose: Anti-SAE2/UBA2 Antibody (monoclonal, 5H11) HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human SAE2/UBA2 recombinant protein (Position: E449-K564).

Isotype: IgG2b

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBA2

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Alternative Name: UBA2

Background:

Background: Ubiquitin-like 1-activating enzyme E1B (UBLE1B) also known as SUMO-activating enzyme subunit 2 (SAE2) is an enzyme that in humans is encoded by the UBA2 gene. Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins

Gene Full Name: ubiquitin like modifier activating enzyme 2

Gene ID: 10054

UniProt: Q9UBT2