SOCS4 antibody (AA 291-440)

Catalog No. ABIN8043777

The Rabbit Polyclonal anti-SOCS4 antibody is suitable to detect SOCS4 in samples from Human. It has been validated for WB.

Quick Overview for SOCS4 antibody (AA 291-440) (ABIN8043777)

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOCS4 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Product Details anti-SOCS4 Antibody

Binding Specificity: AA 291-440

Purpose: Anti-SOCS4 Antibody

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human SOCS4 shares 98% amino acid (aa) sequence identity with mouse SOCS4.

Characteristics: Anti-SOCS4 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SOCS4 recombinant protein (Position: M291-C440). Human SOCS4 shares 98% amino acid (aa) sequence identity with mouse SOCS4.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SOCS4

Target: SOCS4 (Suppressor of Cytokine Signaling 4 (SOCS4))

Alternative Name: SOCS4

Background:

Background: SOCS4, also known as Suppressor of cytokine signaling 4, is mapped to 14q22.1. The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene Full Name: suppressor of cytokine signaling 4

Sequence Similarities: Contains 1 SH2 domain.

Molecular Weight: 51 kDa

Gene ID: 122809

UniProt: Q8WXH5

Pathways: JAK-STAT Signaling, EGFR Signaling Pathway