T-Box 5 antibody (AA 253-518) (Fluoro594)

Catalog No. ABIN8045061

The Rabbit Polyclonal anti-T-Box 5 antibody is suitable to detect T-Box 5 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for T-Box 5 antibody (AA 253-518) (Fluoro594) (ABIN8045061)

Target: T-Box 5 (TBX5)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 5 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-T-Box 5 Antibody (Fluoro594)

Binding Specificity: AA 253-518

Purpose: Anti-TBX5 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TBX5 shares 94.7%,94.4% amino acid (aa) sequence identity with mouse,rat TBX5,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TBX5 recombinant protein (Position: K253-S518). Human TBX5 shares 94.7% and 94.4% amino acid (aa) sequence identity with mouse and rat TBX5, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: TBX5

Background:

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: T-box transcription factor 5

Gene ID: 6910

UniProt: Q99593