TRF2 antibody (AA 81-287) (Fluoro550)

Catalog No. ABIN8045720

This Rabbit Polyclonal antibody specifically detects TRF2 in FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for TRF2 antibody (AA 81-287) (Fluoro550) (ABIN8045720)

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF2 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-TRF2 Antibody (Fluoro550)

Binding Specificity: AA 81-287

Purpose: Anti-TRF2/TERF2 Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TRF2 shares 95.7% amino acid (aa) sequence identity with mouse TRF2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRF2 recombinant protein (Position: A81-K287). Human TRF2 shares 95.7% amino acid (aa) sequence identity with mouse TRF2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Alternative Name: TERF2

Background:

Background: Telomeric repeat-binding factor 2, also known as TERF2, TRF2, or TRBF2, is encoded in humans by the TERF2 gene. This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

Gene Full Name: telomeric repeat binding factor 2

Gene ID: 7014

UniProt: Q15554

Pathways: Cell Division Cycle, Telomere Maintenance