TXNRD2 antibody (C-Term) (HRP)

Catalog No. ABIN8046264

The Rabbit Polyclonal anti-TXNRD2 antibody is suitable to detect TXNRD2 in samples from Human and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for TXNRD2 antibody (C-Term) (HRP) (ABIN8046264)

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNRD2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TXNRD2 Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-TXNRD2 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related rat sequence by three amino acids,and from the related mouse sequence by two amino acids.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TXNRD2, different from the related rat sequence by three amino acids, and from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TXNRD2

Target: TXNRD2 (Thioredoxin Reductase 2 (TXNRD2))

Alternative Name: TXNRD2

Background:

Background: TXNRD2 (Thioredoxin reductase 2), also known as TRXR2, TR3, SELZ, or TR-BETA, Thioredoxin reductases, are selenocysteine (sec)-containing flavoenzymes that maintain thioredoxins, small proteins that catalyze redox reactions, in the reduced state using the reducing power of NADPH. By STS analysis and genomic sequence analysis, respectively, Miranda-Vizuete et al. (1999) and Sun et al. (1999) mapped the TXNRD2 gene to chromosome 22q11.2. Miranda-Vizuete et al. (1999) mapped the mouse gene to chromosome 16. Gasdaska et al. (1999) showed that TXNRD2 was a thioredoxin reductase that could ly reduce proteins such as insulin.

Gene Full Name: thioredoxin reductase 2

Sequence Similarities: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

Gene ID: 10587

UniProt: Q9NNW7

Pathways: Cell RedoxHomeostasis