TOP1MT antibody (AA 18-601) (FITC)

Catalog No. ABIN8047539

The Rabbit Polyclonal anti-TOP1MT antibody is suitable to detect TOP1MT in samples from Human and Mouse. It has been validated for FACS.

Quick Overview for TOP1MT antibody (AA 18-601) (FITC) (ABIN8047539)

Target: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOP1MT antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-TOP1MT Antibody (FITC)

Binding Specificity: AA 18-601

Purpose: Anti-TOP1MT Antibody FITC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TOP1MT recombinant protein (Position: E18-F601).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TOP1MT

Target: TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))

Alternative Name: TOP1MT

Background:

Background: This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: DNA topoisomerase I mitochondrial

Gene ID: 116447

UniProt: Q969P6